Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368923 | 0.92 | KDM4E (0.37) | KDM4EALOX15MAPTSMN1; SMN2BRD4 | |
| SCHEMBL24011573 | 0.91 | KDM4E (0.37) | KDM4EALOX15MAPTSMN1; SMN2BRD4 | |
| SCHEMBL10074197 | 0.89 | NPC1 (0.44) | KDM4EALOX15MAPTSMN1; SMN2BRD4 | |
| SCHEMBL13258695 | 0.89 | THRB (0.38) | KDM4EALOX15MAPTPOLBALDH1A1 | |
| SCHEMBL15472383 | 0.86 | ALOX15 (0.39) | KDM4EALOX15MAPTSMN1; SMN2CRBN | |
| SCHEMBL18747986 | 0.82 | ALOX15 (0.36) | KDM4EALOX15MAPTSMN1; SMN2BRD4 | |
| SCHEMBL14506392 | 0.81 | KDM4E (0.52) | KDM4EALOX15MAPTSMN1; SMN2POLB | |
| SCHEMBL2169035 | 0.81 | KDM4E (0.52) | KDM4EALOX15MAPTSMN1; SMN2POLB | |
| SCHEMBL7850983 | 0.81 | MEN1 (0.38) | KDM4EALOX15MAPTSMN1; SMN2BRD4 | |
| SCHEMBL502389 | 0.81 | ALOX15 (0.46) | KDM4EALOX15MAPTSMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056384-A1 | LENALIDOMIDE SOLVATES AND PROCESSES | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-20 | — | — | WO | disclosed |