Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 11/20 | 0.36 |
| ▸ | PKLR | P30613 | 11/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796098 | 0.83 | CA1 (0.35) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL7901217 | 0.77 | CA1 (0.38) | CA2CA12CA1CA9 | |
| SCHEMBL29469898 | 0.77 | CA1 (0.38) | CA2CA12CA1CA9 | |
| SCHEMBL8875554 | 0.74 | HPGD (0.33) | CA2CA12CA1CA9 | |
| SCHEMBL3776593 | 0.73 | CA1 (0.33) | CA2CA12CA1CA9 | |
| SCHEMBL7901205 | 0.72 | NOTUM (0.32) | — | |
| SCHEMBL7840064 | 0.71 | CYP2D6 (0.38) | — | |
| SCHEMBL8633929 | 0.70 | ALOX5AP (0.36) | PKMCA2CA12CA1CA9 | |
| SCHEMBL4614937 | 0.69 | — | — | |
| SCHEMBL677588 | 0.69 | CA1 (0.52) | PKMPKLRPTGES2CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200931-B1 | FOR CONTROLLING WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-0923578-A1 | 5,6-DIHYDRO- 1,4,2]-DIOXAZIN-SUBSTITUTED (HETERO)ARYL-(OXY-,IMINO-, ALKYL-)-SULPHONYLAMINO(THIO)CARBONYL-HETEROCYCLYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998007721-A1 | 5,6-DIHYDRO-[1,4,2]-DIOXAZIN-SUBSTITUTED (HETERO)ARYL-(OXY-,IMINO-, ALKYL-)-SULPHONYLAMINO(THIO)CARBONYL-HETEROCYCLYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |