Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523642 | 0.77 | — | — | |
| SCHEMBL5734495 | 0.76 | SMN1; SMN2 (0.44) | CYP2D6SMN1; SMN2NPC1HPGDMEN1 | |
| SCHEMBL31325259 | 0.76 | SMN1; SMN2 (0.44) | CYP2D6SMN1; SMN2NPC1HPGDMEN1 | |
| SCHEMBL7901217 | 0.75 | CA1 (0.38) | CYP2C9 | |
| SCHEMBL29469898 | 0.75 | CA1 (0.38) | CYP2C9 | |
| SCHEMBL8633929 | 0.75 | ALOX5AP (0.36) | LMNAMAOB | |
| SCHEMBL8795485 | 0.74 | LMNA (0.39) | SMN1; SMN2NPC1MEN1KMT2ARAB9A | |
| SCHEMBL3175492 | 0.72 | HPGD (0.44) | SMN1; SMN2NPC1HPGDMEN1KMT2A | |
| SCHEMBL2649041 | 0.72 | MEN1 (0.50) | SMN1; SMN2NPC1HPGDMEN1KMT2A | |
| SCHEMBL7911258 | 0.71 | PKM (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066724-C | Substituted arylazadioxacyclo alkene fungicides | BAYER AG (DE) | 2001-06-06 | — | — | CN | disclosed |
| EP-0805805-B1 | SUBSTITUTED ARYLAZADIOXACYCLO ALKENE FUNGICIDES | BAYER AG (DE) | 2001-04-04 | — | — | EP | disclosed |
| US-5852013-A | Substituted arylazadioxacyclo alkene fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| CN-1169148-A | Substituted arylazadioxacycloalkenes as fungicides | BAYER AG (DE) | 1997-12-31 | — | — | CN | disclosed |
| EP-0805805-A1 | SUBSTITUTED ARYLAZADIOXACYCLO ALKENE FUNGICIDES | BAYER AG (DE) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022983-A1 | SUBSTITUTED ARYLAZADIOXACYCLO ALKENE FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | disclosed |