Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159113 | 0.81 | ALDH1A1 (0.56) | SHBGMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3282130 | 0.81 | ERCC5 (0.50) | SHBGMEN1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL27586436 | 0.80 | ALDH1A1 (0.54) | SHBGMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1439664 | 0.77 | MAPT (0.51) | MAPTALDH1A1NPC1GAARAB9A | |
| SCHEMBL2209426 | 0.74 | HDAC1 (0.51) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL7914560 | 0.74 | MAOB (0.63) | MEN1KMT2ACNR2MAOB | |
| SCHEMBL3468116 | 0.73 | ALDH1A1 (0.47) | SHBGMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1395222 | 0.72 | ALDH1A1 (0.53) | SHBGMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6061554 | 0.72 | HDAC1 (0.45) | HDAC1HDAC2GRM5TP53BP1CTSL | |
| SCHEMBL28281104 | 0.72 | GSK3B (0.45) | ALDH1A1HDAC1HDAC2GRM5TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |