Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907452 | 0.86 | MAOB (0.46) | MAOBNR4A2PTPN1 | |
| SCHEMBL7901142 | 0.85 | NR4A2 (0.74) | MAOBNR4A2PTPN1SMPD1SRD5A2 | |
| SCHEMBL2152475 | 0.81 | MAOB (0.73) | MAOBNR4A2PTPN1SMPD1SRD5A2 | |
| SCHEMBL955386 | 0.80 | MAOB (0.52) | MAOBNR4A2PTPN1 | |
| SCHEMBL9526431 | 0.79 | NR4A2 (0.69) | MAOBNR4A2PTPN1SMPD1SRD5A2 | |
| SCHEMBL1800966 | 0.79 | NR4A2 (0.74) | MAOBNR4A2PTPN1SMPD1SRD5A2 | |
| SCHEMBL14190810 | 0.79 | MAOB (0.55) | MAOBNR4A2PTPN1SMPD1NR4A1 | |
| SCHEMBL2503352 | 0.79 | MAOB (0.69) | MAOBNR4A2PTPN1SMPD1SRD5A2 | |
| SCHEMBL31279691 | 0.79 | MAOB (0.69) | MAOBNR4A2PTPN1SMPD1SRD5A2 | |
| SCHEMBL6131764 | 0.78 | PTPN1 (0.79) | MAOBNR4A2PTPN1SMPD1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |