Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.46 |
| ▸ | CA1 | P00915 | 12/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545187 | 0.84 | CHRNA7 (0.49) | CA2CA1CA9CA12CA4 | |
| SCHEMBL7914210 | 0.84 | CA2 (0.46) | CA2CA1CA9CA12CA4 | |
| SCHEMBL11192298 | 0.81 | CA2 (0.48) | CA2CA1CA9CA12CA4 | |
| SCHEMBL11186594 | 0.81 | POLB (0.44) | CA2CA1CA9CA12CA6 | |
| SCHEMBL283890 | 0.80 | CYP3A4 (0.56) | CA2CA1CA9CA12CA4 | |
| SCHEMBL15076431 | 0.80 | CA2 (0.52) | CA2CA1CA9CA12CA4 | |
| SCHEMBL7145771 | 0.78 | CA2 (0.55) | CA2CA1CA9CA12CA4 | |
| SCHEMBL7911338 | 0.77 | GAA (0.63) | CA2CA1CA9CA12CA6 | |
| SCHEMBL2099037 | 0.75 | CES2 (0.61) | CA9CA6CA5ACA14CA5B | |
| SCHEMBL27565289 | 0.75 | CA2 (0.49) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |