Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.46 |
| ▸ | CA1 | P00915 | 15/20 | 0.46 |
| ▸ | CA12 | O43570 | 14/20 | 0.45 |
| ▸ | CA9 | Q16790 | 12/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911333 | 0.86 | CA2 (0.45) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL7913938 | 0.84 | CA2 (0.48) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL7912423 | 0.82 | CA2 (0.46) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL10753390 | 0.81 | CA2 (0.53) | CA2CA1CA12CA9CA6 | |
| SCHEMBL7911327 | 0.80 | CA2 (0.50) | CA2CA1CA12CA9CA6 | |
| SCHEMBL7158564 | 0.80 | CA2 (0.53) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL7911354 | 0.77 | CA2 (0.50) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL2300229 | 0.76 | CA1 (0.70) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL7917822 | 0.76 | CA2 (0.53) | CA2CA1CA12CA9CA6 | |
| SCHEMBL7914154 | 0.75 | CA2 (0.46) | CA2CA1CA12CA9STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |