Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609532 | 0.82 | ALDH1A1 (0.46) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL30450782 | 0.82 | ALDH1A1 (0.46) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL11649733 | 0.82 | ALDH1A1 (0.46) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL9510836 | 0.80 | PTGS1 (0.47) | PTGS1MAPTLMNAMEN1CYP1A2 | |
| SCHEMBL9609552 | 0.80 | CA1 (0.46) | MAPTLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL24554809 | 0.80 | CA1 (0.46) | PTGS1PTGS2MAPTLMNACYP1A2 | |
| SCHEMBL14549176 | 0.80 | ESR1 (0.33) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL3239893 | 0.80 | CA1 (0.46) | PTGS1PTGS2MAPTLMNACYP1A2 | |
| SCHEMBL9510835 | 0.80 | PTGS1 (0.47) | PTGS1MAPTLMNAMEN1CYP1A2 | |
| SCHEMBL13970534 | 0.80 | ALDH1A1 (0.50) | ESR1ESR2PTGS2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127712-A1 | METHOD FOR STEREOSPECIFIC SYNTHESIS OF 2-ENAL AND 2-ENONE COMPOUNDS, AND DEUTERATED COMPOUNDS THEREOF | 复旦大学 | 2022-06-23 | — | — | WO | disclosed |
| CN-107090414-A | Desinsection flavobacterium strain | 马罗内生物创新公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-104508116-B | Pesticidal flavobacterium strains and bioactive compositions, metabolites and uses | 马罗内生物创新公司 | 2017-05-24 | — | — | CN | disclosed |
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |