Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | CSK | P41240 | 1/20 | 0.33 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904943 | 0.81 | KDM4E (0.38) | MAPK1KDM4EL3MBTL1GCKKMT2A | |
| SCHEMBL7904907 | 0.80 | MAPK1 (0.46) | MAPK1KDM4EL3MBTL1ABL1RAB9A | |
| SCHEMBL30746942 | 0.69 | MAPK1 (0.46) | MAPK1KDM4EL3MBTL1ABL1RAB9A | |
| SCHEMBL6413331 | 0.69 | L3MBTL1 (0.54) | MAPK1KDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL6413338 | 0.69 | L3MBTL1 (0.54) | MAPK1KDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL14785605 | 0.68 | RARB (0.56) | MAPK1KDM4EL3MBTL1KMT2A | |
| SCHEMBL31317684 | 0.65 | PTPN1 (0.49) | KDM4EL3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL7081366 | 0.65 | RXRA (0.40) | MAPK1KDM4EL3MBTL1 | |
| SCHEMBL8323003 | 0.64 | GCK (0.60) | KDM4EL3MBTL1GCKRAB9ANPC1 | |
| SCHEMBL8323006 | 0.64 | GCK (0.60) | KDM4EL3MBTL1GCKRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083888-A1 | MULTIBINDING AGENTS THAT MODULATE PPARgamma AND RXR RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063983-A1 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |