Phosphoramidic Acid

Phosphoramidic Acid

SCHEMBL7911730

NP(=O)(O)O.O=P(O)(O)S.O=P(O)(S)S

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
SLC34A1 Q06495 1/20 0.31
FDPS P14324 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5144388 0.87 CA2 (0.42) CA2SLC34A1FDPS
SCHEMBL15044898 0.82
SCHEMBL107367 0.82
Phosphoramidic Acid SCHEMBL30498012 0.82 CA2 (0.46) CA2SLC34A1FDPSALDH1A1
Phosphoramidic Acid SCHEMBL25846 0.82
SCHEMBL2407345 0.82 CA2 (0.46) CA2SLC34A1FDPS
SCHEMBL7820 0.82
SCHEMBL25522 0.82
Phosphoramidic Acid SCHEMBL28135205 0.82 CA2 (0.46) CA2SLC34A1FDPSALDH1A1
Phosphoramidic Acid SCHEMBL28814061 0.80 CA2 (0.31) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232465-B1 NUCLEOTIDE 5'-TRIPHOSPHATE HAVING A REMOVABLE BLOCKING MOIETY PROTECTING THE 3' POSITION AND LINKED TO THE 3' CARBON WHICH IS A HYDROCARBYL, SO A SINGLE PHOSPHODIESTER LINKAGE IS FORMED BETWEEN THE INITIATING SUBSTRATE AND 5' NUCLEOTIDE Hiatt, Andrew C. 2001-05-15 US disclosed
US-6214987-B1 MIXTURE OF A TEMPLATE-INDEPENDENT ENZYME AND A 3' BLOCKED NUCLEOTIDE 5'-TRIPHOSPHATE; EFFICIENT SYNTHESIS OF OLIGO- AND POLYNUCLEOTIDES Hiatt, Andrew C. 2001-04-10 US disclosed
US-5990300-A REACTING NUCLEOSIDE HAVING UNPROTECTED 3' HYDROXY GROUP WITH NUCLEOSIDE 5'-TRIPHOSPHATE HAVING 3' POSITION PROTECTED WITH REMOVABLE BLOCKING MOIETY, IN PRESENCE OF ENZYME WHICH CATALYZES FORMATION OF 5' TO 3' PHOSPHODIESTER LINKAGE Hiatt, Andrew C. (US) 1999-11-23 US disclosed
EP-0781293-A4 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES HIATT ANDREW C ROSE HIATT BIOT (US) 1999-05-26 EP disclosed
US-5872244-A STEPWISE CREATION OF PHOSPHODIESTER BONDS BETWEEN DESIRED NUCLEOSIDES RESULTING IN THE SYNTHESIS OF POLYNUCLEOTIDES HAVING A PREDETERMINED NUCLEOTIDE SEQUENCE Hiatt, Andrew C. (US) 1999-02-16 US disclosed
US-5808045-A Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides Hiatt, Andrew C. (US) 1998-09-15 US disclosed
US-5763594-A DNA AND NUCLEOSIDE-5-TRIPHOSPHATE WITH REMOVABLE BLOCKING GROUPS Hiatt, Andrew C. (US) 1998-06-09 US disclosed
EP-0781293-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES Hiatt, Andrew C. (US) 1997-07-02 EP disclosed
WO-1996007669-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES ROSE-HIATT BIOTECHNOLOGY PARTNERSHIP (US) 1996-03-14 WO disclosed