SCHEMBL2407345

SCHEMBL2407345

O=P(O)(O)S.O=P(O)(O)S

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.46
SLC34A1 Q06495 1/20 0.42
KDM4E B2RXH2 1/20 0.39
MMP2 P08253 1/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FDPS P14324 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TYMS P04818 1/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7820 1.00
Hydrogen Peroxide SCHEMBL7056368 0.94 CA2 (0.42) CA2SLC34A1KDM4EMMP2THRB
SCHEMBL1499953 0.94
SCHEMBL11681547 0.94
SCHEMBL3959241 0.94
SCHEMBL10527922 0.94 CA2 (0.42) CA2SLC34A1KDM4EMMP2THRB
Hydrogen Sulfide SCHEMBL8062675 0.94 CA2 (0.42) CA2SLC34A1KDM4EMMP2THRB
SCHEMBL15467677 0.94
SCHEMBL21044698 0.94 CA2 (0.42) CA2SLC34A1KDM4EMMP2THRB
SCHEMBL8859381 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137543-A1 ADVANCED RNA TARGETING (ARNATAR) ARNATAR THERAPEUTICS, INC (US) 2024-06-27 WO disclosed
US-11866780-B2 Nucleic acid sample enrichment for sequencing applications ILLUMINA CAMBRIDGE LIMITED (GB) 2024-01-09 US disclosed
US-10577646-B2 Nucleotide analogs ABBOTT MOLECULAR INC. (US) 2020-03-03 US disclosed
US-20180320219-A1 NUCLEOTIDE ANALOGS ABBOTT MOLECULAR INC. 2018-11-08 US disclosed
US-20170298431-A1 NUCLEIC ACID SAMPLE ENRICHMENT FOR SEQUENCING APPLICATIONS Ilumina Cambridge Limited (GB) 2017-10-19 US disclosed
EP-2958429-A2 COMPOSITIONS AND METHODS TO INACTIVATE AND/OR REDUCE PRODUCTION OF MICROBIAL TOXINS BIOLOG, INC. (US) 2015-12-30 EP disclosed
WO-2014130655-A2 COMPOSITIONS AND METHODS TO INACTIVATE AND/OR REDUCE PRODUCTION OF MICROBIAL TOXINS BIOLOG, INC. (US) 2014-08-28 WO disclosed
EP-2665359-A1 CROP PLANT-COMPATIBLE HERBICIDAL COMPOSITIONS CONTAINING HERBICIDES AND SAFENERS Rotam Agrochem International Co., Ltd (CN) 2013-11-27 EP disclosed
WO-2012097629-A1 CROP PLANT-COMPATIBLE HERBICIDAL COMPOSITIONS CONTAINING HERBICIDES AND SAFENERS ROTAM AGROCHEM INTERNATIONAL CO., LTD (CN) 2012-07-26 WO disclosed
WO-2011105901-A2 ANTAGONISTS OF COMPLEMENT COMPONENT 9 (C9) AND USES THEREOF ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) 2011-09-01 WO disclosed
WO-2011105900-A2 ANTAGONISTS OF COMPLEMENT COMPONENT 8-ALPHA (C8-ALPHA) AND USES THEREOF ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) 2011-09-01 WO disclosed
US-20050142581-A1 Microrna as ligands and target molecules ISIS PHARMACEUTICALS, INC. 2005-06-30 US disclosed
WO-2005023986-A2 MICRORNA AS LIGANDS AND TARGET MOLECULES ISIS PHARMACEUTICALS, INC. (US) 2005-03-17 WO disclosed
US-5922654-A TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE NSK LTD. (JP) 1999-07-13 US disclosed
US-5506212-A HYBRIDIZE TO DNA AND RNA SEQUENCES; INCREASED STABILITY ISIS PHARMACEUTICALS, INC. (US) 1996-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10577646-B2 Nucleotide analogs NUDT1, NT5C3B, RNGTT CA2 4339/4885SLC34A1 723/4885KDM4E 4150/4885
US-20180320219-A1 NUCLEOTIDE ANALOGS NUDT1, NT5C3B, RNGTT CA2 4339/4885SLC34A1 723/4885KDM4E 4150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.