SCHEMBL7912431

SCHEMBL7912431

CNC(=O)C=Cc1cccc2c1C(=O)NC2=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.48
ALDH1A1 P00352 6/20 0.48
GAA P10253 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
POLB P06746 3/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PSMD14 O00487 1/20 0.43
MMP2 P08253 1/20 0.43
BLM P54132 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
CASP3 P42574 6/20 0.43
CCNC P24863 2/20 0.38
CDK8 P49336 2/20 0.38
PELI1 Q96FA3 2/20 0.37
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
CDK5 Q00535 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9333299 0.79 KDM4E (0.47) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL8577337 0.77 KDM4E (0.45) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL7552794 0.73 KDM4E (0.42) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL7693227 0.73 KDM4E (0.42) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL31229225 0.71 GSK3B (0.48) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL1627401 0.71 GSK3B (0.48) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL28735098 0.71 GSK3B (0.41) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL11358929 0.71 KDM4E (0.54) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL18538464 0.71 BACE1 (0.55) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL626418 0.70 GSK3B (0.46) KDM4EALDH1A1GAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146090-A2 Process for the preparation of pigment dispersion, pigment dispersion obtained by the same, ink jet recording ink comprising the same, and recording method and recording material using the same SEIKO EPSON CORPORATION (JP) 2001-10-17 EP disclosed