Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 6/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | IAPP | P10997 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912431 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8577337 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28735098 | 0.76 | GSK3B (0.41) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL626418 | 0.75 | GSK3B (0.46) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL7693227 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL7552794 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| Iodide SCHEMBL2495412 | 0.74 | GSK3B (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1627401 | 0.73 | GSK3B (0.48) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL31229225 | 0.73 | GSK3B (0.48) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL579203 | 0.72 | GSK3B (0.46) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380669-B1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO CORP (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5130483-A | Antiulcer agents and enzyme inhibitors | TERUMO KABUSHIKI KAISHA (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0380669-A1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-08-08 | — | — | EP | disclosed |