Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.35 |
| ▸ | WNT3A | P56704 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581757 | 0.85 | CTNNB1 (0.34) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL2581753 | 0.85 | CTNNB1 (0.34) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL2589225 | 0.83 | CA9 (0.47) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL27825218 | 0.81 | CTNNB1 (0.34) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL15472216 | 0.81 | NPC1 (0.40) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL2575763 | 0.81 | LTB4R (0.35) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL2575766 | 0.81 | LTB4R (0.35) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL27825249 | 0.80 | CTNNB1 (0.42) | CTNNB1WNT3AMEN1KMT2ANPC1 | |
| SCHEMBL2581752 | 0.79 | CA9 (0.48) | MEN1KMT2ANPC1RAB9ALTB4R | |
| SCHEMBL2461062 | 0.79 | KDM4E (0.42) | CTNNB1WNT3AMEN1KMT2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |