SCHEMBL2589225

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27825249	0.88	CTNNB1 (0.42)	CYSLTR1CYSLTR2LTB4RLTB4R2TBXAS1
	SCHEMBL2581752	0.88	CA9 (0.48)	CA9CYSLTR1CYSLTR2LTB4RLTB4R2
	SCHEMBL2575763	0.85	LTB4R (0.35)	CA9CYSLTR1CYSLTR2LTB4RLTB4R2
	SCHEMBL2575766	0.85	LTB4R (0.35)	CA9CYSLTR1CYSLTR2LTB4RLTB4R2
	SCHEMBL2461164	0.83	CA9 (0.50)	CA9CYSLTR1CYSLTR2LTB4RLTB4R2
	SCHEMBL7912438	0.83	CTNNB1 (0.35)	CA9CYSLTR1CYSLTR2LTB4RLTB4R2
	SCHEMBL15472216	0.83	NPC1 (0.40)	CA9LTB4RLTB4R2CTNNB1WNT3A
	SCHEMBL2588737	0.83	KMT2A (0.43)	CTNNB1WNT3AKMT2AMEN1NPC1
	SCHEMBL2466748	0.83	KMT2A (0.43)	CTNNB1WNT3AKMT2AMEN1NPC1
	SCHEMBL10437031	0.82	CYSLTR1 (0.42)	CYSLTR1CYSLTR2LTB4RLTB4R2TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.