SCHEMBL7912456

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7912511	0.95	RAB9A (0.41)	RAB9ACLK1MAPTNPSR1L3MBTL1
	SCHEMBL2586348	0.91	ESR1 (0.37)	RAB9ACLK1ABCB1CNR1CNR2
	SCHEMBL7910678	0.88	RAB9A (0.40)	RAB9ACLK1MAPTNPSR1L3MBTL1
	SCHEMBL12160478	0.86	ESR1 (0.38)	RAB9ACLK1ABCB1CNR1CNR2
	SCHEMBL2578934	0.85	ABCB1 (0.33)	RAB9ACLK1ABCB1CNR1CNR2
	SCHEMBL2584574	0.84	ABCB1 (0.32)	ABCB1CNR1CNR2
	SCHEMBL2579066	0.83	POLB (0.44)	MAPTALDH1A1GAALMNAPOLB
	SCHEMBL2575667	0.82	KDM4E (0.35)	MAPTABCB1CNR1CNR2ALDH1A1
	SCHEMBL2587899	0.81	ABCB1 (0.30)	ABCB1
	SCHEMBL7913573	0.81	HRH3 (0.37)	ABCB1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.