Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771060 | 1.00 | MME (0.33) | MMERAB9ALTA4H | |
| SCHEMBL9614199 | 0.73 | CYP2D6 (0.36) | MMELTA4H | |
| SCHEMBL13715066 | 0.72 | ARG1 (0.34) | — | |
| SCHEMBL8016763 | 0.72 | ARG1 (0.34) | — | |
| SCHEMBL13715084 | 0.67 | ARG1 (0.30) | — | |
| SCHEMBL6051929 | 0.66 | CYP2D6 (0.31) | — | |
| SCHEMBL3665319 | 0.64 | PARP1 (0.31) | — | |
| SCHEMBL3665322 | 0.64 | PARP1 (0.31) | — | |
| SCHEMBL14534806 | 0.60 | — | — | |
| SCHEMBL8526197 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779150-B | Preparation method of degarelix and intermediate thereof | 费森尤斯卡比依普莎姆责任有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-108779150-A | The Preparation Method And Their Intermediate of Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-4Aph(Hor)-D-4Aph(Cbm)-Leu-Lys(iPr)-Pro-D-Ala-NH2 | 费森尤斯卡比依普莎姆责任有限公司 | 2018-11-09 | — | — | CN | disclosed |
| US-6214798-B1 | POLYPEPTIDES | FERRING BV (NL) | 2001-04-10 | — | — | US | disclosed |
| EP-1003774-A1 | GnRH ANTAGONISTS BEING MODIFIED IN POSITIONS 5 AND 6 | FERRING B.V. (NL) | 2000-05-31 | — | — | EP | disclosed |
| EP-0973801-A1 | GnRH ANTAGONISTS | FERRING B.V. (NL) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046634-A1 | GnRH ANTAGONISTS BEING MODIFIED IN POSITIONS 5 AND 6 | FERRING B.V. (NL) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046635-A1 | GnRH ANTAGONISTS | FERRING BV (NL) | 1998-10-22 | — | — | WO | disclosed |
| WO-1997022622-A1 | BETIDE-SUBSTITUTED GNRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-06-26 | — | — | WO | disclosed |
| EP-0500695-A1 | GnRH ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991006543-A1 | GnRH ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1991-05-16 | — | — | WO | disclosed |