Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912477 | 0.73 | MME (0.33) | MMELTA4H | |
| SCHEMBL10771060 | 0.73 | MME (0.33) | MMELTA4H | |
| SCHEMBL23128322 | 0.64 | SLC6A2 (0.43) | CYP2D6SLC6A2SLC6A4SLC6A3MME | |
| SCHEMBL24636252 | 0.62 | ARG1 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3ARG1 | |
| SCHEMBL24636199 | 0.62 | ARG1 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3ARG1 | |
| SCHEMBL24636215 | 0.62 | ARG1 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3ARG1 | |
| SCHEMBL24636213 | 0.62 | ARG1 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3ARG1 | |
| SCHEMBL1025477 | 0.60 | ARG1 (0.41) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL1025995 | 0.60 | ARG1 (0.41) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL20814139 | 0.60 | ARG1 (0.38) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448687-A4 | THERAPEUTIC DECAPEPTIDES | — | 1992-04-01 | — | — | EP | claimed |
| EP-0448687-A1 | THERAPEUTIC DECAPEPTIDES | The Administrators of The Tulane Educational Fund (US) | 1991-10-02 | — | — | EP | claimed |
| WO-1991005563-A1 | THERAPEUTIC DECAPEPTIDES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1991-05-02 | — | — | WO | claimed |