Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862441 | 1.00 | MAPT (0.36) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL23293607 | 0.89 | MAPT (0.39) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL8351594 | 0.86 | — | — | |
| SCHEMBL14169594 | 0.83 | CA1 (0.37) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL10570611 | 0.75 | KMT2A (0.42) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL24189214 | 0.68 | CA1 (0.30) | — | |
| SCHEMBL9973375 | 0.68 | — | — | |
| SCHEMBL16802426 | 0.68 | MAPT (0.33) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL24799805 | 0.68 | CA1 (0.40) | MAPTALDH1A1LMNAGAANPC1 | |
| SCHEMBL6722036 | 0.68 | MAPT (0.42) | MAPTALDH1A1LMNAGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207862-B1 | PRECURSORS ARE CHIRAL 4-HYDROXYCARBOXAMIDES, 4-HYDROXYHYDROXAMIC ACIDS, OR 4-HYDROXYHYDRAZIDES PRODUCED FROM GAMMA-LACTONES, WHICH IN TURN ARE DERIVED FROM 1,4-DIOLS BY STEREOSELECTIVE OXIDATION, | BIOCATALYTICS, INC. | 2001-03-27 | — | — | US | disclosed |