Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924526 | 0.90 | MAPT (0.33) | MAPTKMT2AKCNN4ALDH1A1ALOX15 | |
| SCHEMBL8400095 | 0.73 | KIF11 (0.45) | ALDH1A1KIF11LMNAKDM4EADRA2A | |
| SCHEMBL10417502 | 0.72 | KCNN4 (0.47) | MAPTKMT2AKCNN4ALDH1A1ALOX15 | |
| SCHEMBL10007041 | 0.69 | KCNN4 (0.43) | MAPTKMT2AKCNN4ALDH1A1KIF11 | |
| SCHEMBL11297836 | 0.69 | ALDH1A1 (0.38) | MAPTKMT2AKCNN4ALDH1A1ALOX15 | |
| SCHEMBL10768854 | 0.69 | ALDH1A1 (0.38) | MAPTKMT2AKCNN4ALDH1A1ALOX15 | |
| SCHEMBL10006934 | 0.69 | KCNN4 (0.43) | MAPTKMT2AKCNN4ALDH1A1KIF11 | |
| SCHEMBL15517407 | 0.68 | KIF11 (0.56) | KMT2AKIF11LMNA | |
| SCHEMBL7485618 | 0.68 | KDM4E (0.38) | KCNN4KIF11LMNAKDM4EMAPK1 | |
| SCHEMBL6039133 | 0.68 | KIF11 (0.46) | KIF11LMNACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187913-B1 | Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method | GENSET (FR) | 2001-02-13 | — | — | US | disclosed |