Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | FABP2 | P12104 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760864 | 0.87 | CLCN2 (0.58) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL7902075 | 0.79 | CLCN2 (0.57) | CLCN2ALDH1A1KDM4EPTGS2MEN1 | |
| SCHEMBL7910144 | 0.79 | CLCN2 (0.59) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL9260616 | 0.77 | CLCN2 (0.57) | CLCN2ALDH1A1PKMKDM4EPTGS2 | |
| SCHEMBL9260755 | 0.74 | CLCN2 (0.57) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL24021595 | 0.72 | CLCN2 (0.63) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL8978544 | 0.72 | ALDH1A1 (1.00) | ALDH1A1PKMAPOBEC3GKDM4EMEN1 | |
| SCHEMBL2760397 | 0.70 | PTGS2 (0.65) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL8611982 | 0.70 | CLCN2 (0.54) | CLCN2PTGS2MEN1MAPK1KMT2A | |
| SCHEMBL9863251 | 0.68 | CLCN2 (0.55) | CLCN2PTGS2MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211209-B1 | NONDEGRADING TISSUES, DRUGS, DIPHENYLAMINES | WARNER-LAMBERT COMPANY | 2001-04-03 | — | — | US | claimed |
| US-6211209-B1 | NONDEGRADING TISSUES, DRUGS, DIPHENYLAMINES | WARNER-LAMBERT COMPANY | 2001-04-03 | — | — | US | disclosed |