Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916794 | 0.99 | SLC9A1 (0.61) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL927184 | 0.99 | SLC9A1 (0.61) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| Maleic Acid SCHEMBL7916788 | 0.92 | SLC9A1 (0.54) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7910322 | 0.83 | SLC9A1 (0.43) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7913231 | 0.83 | SLC9A1 (0.41) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL927183 | 0.83 | SLC9A1 (0.45) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7916809 | 0.83 | SLC9A1 (0.45) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7913104 | 0.82 | KDM4E (0.45) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7902791 | 0.82 | SLC9A1 (0.45) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7916722 | 0.82 | SLC9A1 (0.45) | SLC9A1SMN1; SMN2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |