Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916794 | 0.85 | SLC9A1 (0.61) | SLC9A1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL927184 | 0.85 | SLC9A1 (0.61) | SLC9A1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7912931 | 0.83 | SLC9A1 (0.59) | SLC9A1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7913231 | 0.80 | SLC9A1 (0.41) | SLC9A1ACHERAB9ASMN1; SMN2KDM4E | |
| Maleic Acid SCHEMBL7916788 | 0.79 | SLC9A1 (0.54) | SLC9A1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL927447 | 0.77 | SLC9A1 (0.39) | SLC9A1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7911358 | 0.76 | SLC9A1 (0.38) | SLC9A1ACHERAB9ASMN1; SMN2TSHR | |
| SCHEMBL7913350 | 0.76 | SLC9A1 (0.37) | SLC9A1ACHESMN1; SMN2KDM4EMAPT | |
| SCHEMBL7910373 | 0.73 | ACHE (0.56) | ACHENPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL928773 | 0.72 | SLC9A1 (0.35) | SLC9A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |