Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ANTXR2 | P58335 | 3/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913146 | 1.00 | TSHR (0.42) | TSHRANTXR2F11LMNAELANE | |
| SCHEMBL7914158 | 1.00 | TSHR (0.42) | TSHRANTXR2F11LMNAELANE | |
| SCHEMBL8616099 | 0.83 | TSHR (0.62) | TSHRLMNAPTPN1KMT2ACYP2D6 | |
| SCHEMBL7913115 | 0.82 | FKBP1A (0.32) | ELANEKMT2A | |
| SCHEMBL7905755 | 0.82 | CA12 (0.48) | TSHRANTXR2LMNAALDH1A1CA12 | |
| SCHEMBL8507736 | 0.82 | CA12 (0.53) | TSHRLMNAALDH1A1CA12CA1 | |
| SCHEMBL7995830 | 0.82 | CA12 (0.53) | TSHRLMNAALDH1A1CA12CA1 | |
| SCHEMBL7905847 | 0.82 | CA12 (0.53) | TSHRLMNAALDH1A1CA12CA1 | |
| SCHEMBL7455747 | 0.82 | CA12 (0.53) | TSHRLMNAALDH1A1CA12CA1 | |
| SCHEMBL7986114 | 0.82 | CA12 (0.53) | TSHRLMNAALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274716-B1 | COMPRISE DISACCHARIDES AND TRISACCHARIDES COVALENTLY BONDED TO LIPID OR LIPID MIMETIC THROUGH PHOSPHOROUS LINKAGE; SCREENED FOR ANTI-MICROBIAL ACTIVITY BY CONTACTING THEM WITH CULTURE OF MICROBES AND MONITORING THE GROWTH RATE | ADVANCED MEDICINE, INC. | 2001-08-14 | — | — | US | disclosed |
| US-6207820-B1 | SOLID PHASE SYNTHESIS BY LINKING ACCEPTOR MONOSACCHARIDE TO SUPPORT FORMING CARBOXYLATE OR CARBOXYAMIDE LINKAGE, COVALENTLY LINKING DONOR SACCHARIDE BY O-GLYCOSIDIC LINKAGE, COUPLING LIPOPHOSPHOGLYCERATE MIMETIC, CLEAVING FROM SUPPORT | INCARA RESEARCH LABORATORIES | 2001-03-27 | — | — | US | disclosed |
| US-6114309-A | REACTION PRODUCT OF MONOSACCHARIDE, DISACCHARIDE AND LIPOPHOSPHOGLYCERATE MINETIC | INCARA RESEARCH LABORATORIES (US) | 2000-09-05 | — | — | US | disclosed |