Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913158 | 0.82 | TSHR (0.42) | ELANEKMT2A | |
| SCHEMBL7914158 | 0.82 | TSHR (0.42) | ELANEKMT2A | |
| SCHEMBL7913146 | 0.82 | TSHR (0.42) | ELANEKMT2A | |
| SCHEMBL8009738 | 0.80 | CA12 (0.39) | FKBP1AELANEGAAMAPTMEN1 | |
| SCHEMBL7916070 | 0.80 | CA12 (0.39) | FKBP1AELANEGAAMAPTMEN1 | |
| SCHEMBL7995825 | 0.72 | ELANE (0.32) | ELANE | |
| SCHEMBL7985818 | 0.72 | ELANE (0.32) | ELANE | |
| SCHEMBL3780804 | 0.70 | LGALS9 (0.43) | GAAMEN1KMT2A | |
| SCHEMBL14268496 | 0.70 | LGALS9 (0.43) | GAAMEN1KMT2A | |
| SCHEMBL14293976 | 0.70 | LGALS9 (0.43) | GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207820-B1 | SOLID PHASE SYNTHESIS BY LINKING ACCEPTOR MONOSACCHARIDE TO SUPPORT FORMING CARBOXYLATE OR CARBOXYAMIDE LINKAGE, COVALENTLY LINKING DONOR SACCHARIDE BY O-GLYCOSIDIC LINKAGE, COUPLING LIPOPHOSPHOGLYCERATE MIMETIC, CLEAVING FROM SUPPORT | INCARA RESEARCH LABORATORIES | 2001-03-27 | — | — | US | disclosed |
| US-6114309-A | REACTION PRODUCT OF MONOSACCHARIDE, DISACCHARIDE AND LIPOPHOSPHOGLYCERATE MINETIC | INCARA RESEARCH LABORATORIES (US) | 2000-09-05 | — | — | US | disclosed |