Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912966 | 0.82 | KDM4E (0.43) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL31345629 | 0.80 | KDM4E (0.50) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL927885 | 0.80 | SLC9A1 (0.60) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL26617630 | 0.80 | KDM4E (0.50) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL26617915 | 0.80 | KDM4E (0.50) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL30681912 | 0.79 | KDM4E (0.49) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7911369 | 0.79 | KDM4E (0.49) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7913301 | 0.79 | KDM4E (0.49) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL26618036 | 0.79 | KDM4E (0.49) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL10472947 | 0.79 | KDM4E (0.51) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |