Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912186 | 0.86 | MAPT (0.55) | KDREGFRTP53MAPTCA1 | |
| SCHEMBL7913328 | 0.85 | KDR (0.69) | KDRABCG2TP53MAPTCA1 | |
| SCHEMBL7918683 | 0.84 | KDR (0.60) | KDRABCG2EGFRTP53MAPT | |
| SCHEMBL7914911 | 0.78 | MEN1 (0.52) | TP53MAPTLMNA | |
| SCHEMBL7913393 | 0.78 | EGFR (0.47) | KDREGFRMAPTCA9LMNA | |
| SCHEMBL7913392 | 0.77 | ABCG2 (0.58) | KDRABCG2EGFRTP53MAPT | |
| SCHEMBL8014060 | 0.77 | MAPT (0.66) | KDRABCG2EGFRMAPTCA9 | |
| SCHEMBL7918376 | 0.75 | KDR (0.44) | KDREGFRTP53MAPTCA1 | |
| SCHEMBL7913364 | 0.75 | KDR (0.58) | KDRABCG2EGFRTP53MAPT | |
| SCHEMBL7905464 | 0.75 | MAPT (0.63) | KDRTP53MAPTCA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |