Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 5/20 | 0.62 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915171 | 0.88 | NPSR1 (0.61) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL7914864 | 0.88 | NPSR1 (0.61) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL7913341 | 0.87 | NPSR1 (0.67) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL7915141 | 0.84 | MAPT (0.50) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL28681902 | 0.83 | HPGD (0.56) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL3021512 | 0.83 | MAPT (0.81) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL7918628 | 0.83 | MAPT (0.81) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL28682662 | 0.83 | HPGD (0.55) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL15783190 | 0.81 | KDR (0.70) | MAPTLMNAALDH1A1L3MBTL1THRB | |
| SCHEMBL3024303 | 0.81 | MAPT (1.00) | MAPTLMNAALDH1A1L3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |