Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.67 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914864 | 0.91 | NPSR1 (0.61) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7915171 | 0.91 | NPSR1 (0.61) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7913368 | 0.87 | MAPT (0.68) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7918607 | 0.87 | NPSR1 (0.51) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7918566 | 0.86 | ENPP3 (0.76) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7918523 | 0.85 | MAPT (0.61) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7918550 | 0.84 | THRB (0.58) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7918655 | 0.82 | MAPT (0.69) | NPSR1KDRGAAKDM4EALDH1A1 | |
| SCHEMBL7904940 | 0.82 | ENPP3 (0.70) | NPSR1ENPP3KDRGAATHRB | |
| SCHEMBL7905029 | 0.82 | NPSR1 (0.73) | NPSR1ENPP3KDRGAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |