Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PDE1A | P54750 | 1/20 | 0.51 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915171 | 0.95 | NPSR1 (0.61) | NPSR1GAAKDM4ETHRBHTT | |
| SCHEMBL7913341 | 0.91 | NPSR1 (0.67) | NPSR1GAAKDM4ETHRBHTT | |
| SCHEMBL7913368 | 0.88 | MAPT (0.68) | NPSR1GAAKDM4ETHRBHTT | |
| SCHEMBL7918655 | 0.87 | MAPT (0.69) | NPSR1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL7914861 | 0.86 | MAPT (0.60) | NPSR1GAAKDM4ETHRBMAPT | |
| SCHEMBL12696197 | 0.85 | HSD11B1 (0.57) | NPSR1KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7912120 | 0.85 | MAPT (0.59) | NPSR1KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL7915153 | 0.84 | MAPT (0.61) | NPSR1GAAKDM4ETHRBHTT | |
| SCHEMBL7915070 | 0.81 | NPSR1 (0.67) | NPSR1GAAKDM4ETHRBHTT | |
| SCHEMBL7918550 | 0.80 | THRB (0.58) | NPSR1GAATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |