Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.66 |
| ▸ | ESR1 | P03372 | 7/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | BCR | P11274 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767331 | 0.80 | ESR1 (0.53) | KIF11ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL13104729 | 0.79 | ESR1 (0.67) | KIF11ESR1ESR2ABL1ABCB1 | |
| SCHEMBL5099663 | 0.79 | ESR1 (0.62) | KIF11ESR1ESR2ABL1ABCB1 | |
| SCHEMBL9280477 | 0.79 | ESR1 (0.62) | KIF11ESR1ESR2ABL1ABCB1 | |
| SCHEMBL759007 | 0.79 | CA12 (0.41) | KIF11ESR1ESR2ABL1ABCB1 | |
| SCHEMBL13002538 | 0.78 | CYP11B1 (0.46) | KIF11AR | |
| SCHEMBL28835874 | 0.78 | KIF11 (0.60) | KIF11ESR1ESR2ABL1ABCB1 | |
| SCHEMBL13863713 | 0.78 | CYP11B1 (0.46) | KIF11AR | |
| SCHEMBL30332163 | 0.77 | ESR1 (0.44) | KIF11ESR1ESR2ARHSD17B1 | |
| SCHEMBL14087816 | 0.77 | NQO1 (0.54) | KIF11ESR1ESR2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820976-B1 | FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORP (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-6051288-A | LARGE DIELECTRIC ANISOTROPY, SMALL CHANGE IN THRESHOLD VOLTAGE DEPENDING ON TEMPERATURE, AND AN IMPROVED SOLUBILITY TO OTHER LIQUID CRYSTAL MATERIALS AT LOW TEMPERATURES | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0820976-A1 | FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |