SCHEMBL759007

SCHEMBL759007

Oc1cc(F)c(C(F)(F)F)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
KIF11 P52732 2/20 0.39
BACE1 P56817 1/20 0.37
ESR1 P03372 5/20 0.34
ESR2 Q92731 5/20 0.34
PTGS1 P23219 1/20 0.34
DAO P14920 1/20 0.34
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
NQO1 P15559 1/20 0.31
ABL1 P00519 1/20 0.31
ABCB1 P08183 1/20 0.31
BCR P11274 1/20 0.31
HCAR1 Q9BXC0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30332163 0.87 ESR1 (0.44) CA12CA1CA9TAAR1KIF11
SCHEMBL26709499 0.84 ESR2 (0.38) CA12CA1CA9TAAR1KIF11
SCHEMBL16193055 0.84 CYP3A4 (0.39) CA12CA1CA9TAAR1KIF11
SCHEMBL14087816 0.82 NQO1 (0.54) CA12CA1CA9KIF11ESR1
SCHEMBL7913380 0.79 KIF11 (0.66) KIF11ESR1ESR2ABL1ABCB1
SCHEMBL24920131 0.79 CA1 (0.39) CA12CA1CA9TAAR1KIF11
SCHEMBL14767331 0.77 ESR1 (0.53) KIF11ESR1ESR2
SCHEMBL4218653 0.77 DAO (0.36) CA12CA1CA9DAO
SCHEMBL1472949 0.76 GABRA1 (0.46) CA12CA1CA9TAAR1BACE1
SCHEMBL1473762 0.75 GABRA1 (0.36) CA12CA1CA9TAAR1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4263749-B1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2025-06-18 EP disclosed
CN-117164436-A Method for synthesizing polyfluorophenol by lanthanum cerium copper catalysis 浙江大学衢州研究院 2023-12-05 CN disclosed
CN-117024254-A Synthesis method of polyfluorophenol 浙江大学衢州研究院 2023-11-10 CN disclosed
EP-4263749-A1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES Merck Patent GmbH (DE) 2023-10-25 EP disclosed
CN-116670255-A Dibenzofuran and dibenzothiophene derivatives 默克专利股份有限公司 2023-08-29 CN disclosed
WO-2022128847-A1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022128847-A1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
CN-105906490-B Liquid crystalline compound having vinylidene group, liquid crystal composition, and liquid crystal display element 捷恩智株式会社 2021-06-29 CN disclosed
CN-105121596-B Mesogenic compounds, liquid-crystalline medium and liquid-crystal display 默克专利股份有限公司 2021-03-12 CN disclosed
CN-109652094-B Preparation method of difluoromethyl ether bridged liquid crystal monomer 西安彩晶光电科技股份有限公司 2020-07-14 CN disclosed
US-7722783-B2 Optically isotropic liquid crystal medium and optical device CHISSO CORPORATION (JP) 2010-05-25 US disclosed
EP-2098583-A2 Optically isotropic liquid crystal medium and optical device Chisso Corporation (JP) 2009-09-09 EP disclosed
EP-2098583-A2 Optically isotropic liquid crystal medium and optical device Chisso Corporation (JP) 2009-09-09 EP disclosed
US-20090135368-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-05-28 US disclosed
US-20090135368-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-05-28 US disclosed
US-20090135368-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-05-28 US disclosed
EP-0820976-B1 FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE CHISSO CORP (JP) 2001-02-21 EP disclosed
US-6051288-A LARGE DIELECTRIC ANISOTROPY, SMALL CHANGE IN THRESHOLD VOLTAGE DEPENDING ON TEMPERATURE, AND AN IMPROVED SOLUBILITY TO OTHER LIQUID CRYSTAL MATERIALS AT LOW TEMPERATURES CHISSO CORPORATION (JP) 2000-04-18 US disclosed
EP-0820976-A1 FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 1998-01-28 EP disclosed
EP-0272533-A2 Substituted phenoxypyridines BAYER AG (DE) 1988-06-29 EP disclosed