Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913269 | 0.93 | ROCK2 (0.34) | CYP2C9HCAR2S1PR1ROCK2 | |
| SCHEMBL795594 | 0.89 | ROCK2 (0.34) | FFAR1CYP2C9HCAR2S1PR1ROCK2 | |
| SCHEMBL29922027 | 0.87 | ROCK2 (0.34) | FFAR1CYP2C9HCAR2S1PR1ROCK2 | |
| SCHEMBL1150210 | 0.87 | ROCK2 (0.34) | FFAR1CYP2C9HCAR2S1PR1ROCK2 | |
| SCHEMBL7911578 | 0.86 | BCL2 (0.35) | FFAR1CYP2C9HCAR2S1PR1ROCK2 | |
| SCHEMBL7903246 | 0.86 | KDM4E (0.35) | FFAR1S1PR1ROCK2RAD52 | |
| SCHEMBL7917122 | 0.86 | ROCK2 (0.34) | FFAR1CYP2C9HCAR2S1PR1ROCK2 | |
| SCHEMBL7913240 | 0.86 | ROCK2 (0.34) | FFAR1NR1H4CYP2C9HCAR2S1PR1 | |
| SCHEMBL7903224 | 0.85 | CYP19A1 (0.34) | FFAR1CYP2C9HCAR2ROCK2 | |
| SCHEMBL7911557 | 0.85 | FFAR1 (0.35) | FFAR1ROCK2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |