Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585371 | 0.83 | FAAH (0.41) | SLC6A4HCRTR1HCRTR2FAAHS1PR5 | |
| SCHEMBL7914395 | 0.82 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DSMPD1 | |
| SCHEMBL7913482 | 0.82 | PDE4B (0.46) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL7913460 | 0.81 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL7919822 | 0.79 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL7916316 | 0.79 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL7906247 | 0.79 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL6584230 | 0.78 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DHCRTR1 | |
| SCHEMBL7916035 | 0.77 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7916410 | 0.77 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |