SCHEMBL7913486

SCHEMBL7913486

c1cnc2ccc(-c3ccc4ccccc4n3)cc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.65
NPC1 O15118 7/20 0.65
POLB P06746 2/20 0.65
ALDH1A1 P00352 7/20 0.57
AR P10275 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
DYRK1A Q13627 1/20 0.53
KDM4E B2RXH2 5/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
MAPT P10636 4/20 0.51
HPGD P15428 2/20 0.51
TP53 P04637 2/20 0.51
HSD17B10 Q99714 2/20 0.51
GMNN O75496 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914859 0.90 NPC1 (0.58) RAB9ANPC1POLBALDH1A1AR
SCHEMBL30938000 0.90 NPC1 (0.58) RAB9ANPC1POLBALDH1A1AR
SCHEMBL17945843 0.85 NPC1 (0.48) RAB9ANPC1POLBALDH1A1AR
SCHEMBL23016081 0.85 NPC1 (0.58) RAB9ANPC1POLBARCYP3A4
SCHEMBL19227053 0.85 RAB9A (0.56) RAB9ANPC1POLBALDH1A1AR
2-Phenylquinoline SCHEMBL27720052 0.84 NPC1 (0.65) RAB9ANPC1POLBALDH1A1AR
SCHEMBL23016156 0.84 NPC1 (0.49) RAB9ANPC1POLBALDH1A1AR
SCHEMBL23016080 0.83 NPC1 (0.60) RAB9ANPC1POLBALDH1A1AR
SCHEMBL23016176 0.83 POLB (0.60) RAB9ANPC1POLBALDH1A1AR
SCHEMBL23016166 0.82 NPC1 (0.50) RAB9ANPC1POLBALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718277-B2 Electronic devices comprising organic iridium compositions GENERAL ELECTRIC COMPANY (US) 2010-05-18 US disclosed
US-7718277-B2 Electronic devices comprising organic iridium compositions GENERAL ELECTRIC COMPANY (US) 2010-05-18 US disclosed
US-7718087-B2 Organic iridium compositions and their use in electronic devices GENERAL ELECTRIC COMPANY (US) 2010-05-18 US disclosed
US-7718087-B2 Organic iridium compositions and their use in electronic devices GENERAL ELECTRIC COMPANY (US) 2010-05-18 US disclosed
US-7704610-B2 organic light emitting device comprising deuterated organic iridium complex; optoelectronic devices, photovoltaic devices; enhanced color properties and light output efficiencies GENERAL ELECTRIC COMPANY (US) 2010-04-27 US disclosed
US-7704610-B2 organic light emitting device comprising deuterated organic iridium complex; optoelectronic devices, photovoltaic devices; enhanced color properties and light output efficiencies GENERAL ELECTRIC COMPANY (US) 2010-04-27 US disclosed
US-20100090586-A1 ELECTRONIC DEVICES COMPRISING ORGANIC IRIDIUM COMPOSITIONS GENERAL ELECTRIC COMPANY 2010-04-15 US disclosed
US-20100090586-A1 ELECTRONIC DEVICES COMPRISING ORGANIC IRIDIUM COMPOSITIONS GENERAL ELECTRIC COMPANY 2010-04-15 US disclosed
US-7695640-B2 Organic iridium compositions and their use in electronic devices GENERAL ELECTRIC COMPANY (US) 2010-04-13 US disclosed
US-7695640-B2 Organic iridium compositions and their use in electronic devices GENERAL ELECTRIC COMPANY (US) 2010-04-13 US disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
US-4981949-A POLYQUINOLINES AND CATALYST FOR POLYMERIZATION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-01-01 US disclosed
US-4971938-A TETRAHYDROQUINOLINE-METAL SULFIDE COMPOSITION; CATALYSTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1990-11-20 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed