SCHEMBL7914859

SCHEMBL7914859

c1cnc2cc(-c3ccc4ccccc4n3)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.58
RAB9A P51151 9/20 0.58
AR P10275 2/20 0.58
CYP3A4 P08684 2/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2C19 P33261 2/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
ALDH1A1 P00352 7/20 0.55
KDM4E B2RXH2 5/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
MAPT P10636 3/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
THPO P40225 1/20 0.54
BLM P54132 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30938000 1.00 NPC1 (0.58) NPC1RAB9AARCYP3A4CYP1A2
SCHEMBL7913486 0.90 RAB9A (0.65) NPC1RAB9AARCYP3A4CYP1A2
SCHEMBL19227053 0.88 RAB9A (0.56) NPC1RAB9AARCYP3A4CYP1A2
SCHEMBL20127212 0.85 NPC1 (0.53) NPC1RAB9AARCYP3A4CYP1A2
SCHEMBL21133668 0.85 NPC1 (0.58) NPC1RAB9ACYP1A2CYP2C19MEN1
SCHEMBL24621710 0.84 ALDH1A1 (0.46) NPC1RAB9AARCYP3A4CYP1A2
SCHEMBL21390594 0.84 NPC1 (0.45) NPC1RAB9AARCYP3A4CYP1A2
SCHEMBL21481208 0.84 ALDH1A1 (0.49) NPC1RAB9ACYP1A2CYP2C19MEN1
SCHEMBL9838799 0.84 ALDH1A1 (0.52) NPC1RAB9ACYP3A4CYP1A2CYP2C19
SCHEMBL31121089 0.84 ALDH1A1 (0.52) NPC1RAB9ACYP3A4CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710662-B Heterocyclic compound and organic light-emitting device including the same LT素材株式会社 2024-06-18 CN disclosed
US-20220165962-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LT MATERIALS CO., LTD. (KR) 2022-05-26 US disclosed
US-20220165962-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LT MATERIALS CO., LTD. (KR) 2022-05-26 US disclosed
CN-113710662-A Heterocyclic compound and organic light-emitting device including same LT素材株式会社 2021-11-26 CN disclosed
WO-2021025356-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME 엘티소재주식회사 2021-02-11 WO disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0355575-B1 Method of preventing polymer scale formation SHINETSU CHEMICAL CO (JP) 1994-11-02 EP disclosed
US-5298220-A Forming a coating of a solution containing anioic and cationic dyes and water insoluble organonitrogen compound, drying SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-03-29 US disclosed
US-5196164-A During addition polymerization, wall coating of anionic dye and cationic dye and organonitrogen compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-03-23 US disclosed
EP-0355575-A2 Method of preventing polymer scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1990-02-28 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220165962-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CRY1, CYP1A1, CYP1B1 NPC1 2848/4885RAB9A 2681/4885AR 1942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.