SCHEMBL7913541

SCHEMBL7913541

ClCc1c(-c2ccccc2)ccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.53
HSD17B10 Q99714 5/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
ALDH1A1 P00352 6/20 0.41
CYP2A6 P11509 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 5/20 0.40
HPGD P15428 3/20 0.40
GAA P10253 3/20 0.40
GLA P06280 1/20 0.40
MAPT P10636 5/20 0.39
KMT2A Q03164 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
MEN1 O00255 1/20 0.39
MPI P34949 1/20 0.39
CYP1B1 Q16678 2/20 0.38
CYP1A1 P04798 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10898978 0.86 L3MBTL1 (0.47) L3MBTL1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL7913584 0.82 HSD17B10 (0.47) L3MBTL1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL11614266 0.81 L3MBTL1 (0.53) L3MBTL1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL2152213 0.81 HSD17B10 (0.41) L3MBTL1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL15345570 0.81 ALDH1A1 (0.56) L3MBTL1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL7648626 0.81 HSD17B10 (0.41) L3MBTL1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL6915578 0.81 NCEH1 (0.43) HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL7143018 0.79 HSD17B10 (0.44) HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL7653838 0.78 HSD17B10 (0.39) L3MBTL1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL1537096 0.78 ALDH1A1 (0.50) HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed