Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917586 | 0.90 | LIPG (0.41) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7903804 | 0.90 | KMT2A (0.40) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7913646 | 0.88 | ALDH1A1 (0.43) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7903470 | 0.85 | KMT2A (0.39) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7911982 | 0.83 | KMT2A (0.41) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7913585 | 0.81 | KMT2A (0.40) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7917584 | 0.80 | KMT2A (0.38) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7911168 | 0.79 | KMT2A (0.40) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7913826 | 0.79 | ALDH1A1 (0.43) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7917393 | 0.78 | ALDH1A1 (0.44) | KMT2AHTTSMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640578-B2 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0640578-B1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0640578-A1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | Chisso Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |