Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349207 | 0.72 | GSK3A (0.37) | GSK3AGSK3B | |
| SCHEMBL725528 | 0.69 | GSK3A (0.39) | GSK3AGSK3B | |
| SCHEMBL29427881 | 0.69 | GSK3A (0.39) | GSK3AGSK3B | |
| SCHEMBL30483673 | 0.68 | HTT (0.32) | HSD17B10HTTKMT2A | |
| SCHEMBL28642002 | 0.65 | CMA1 (0.43) | GSK3AGSK3B | |
| SCHEMBL29750384 | 0.65 | GSK3A (0.39) | GSK3AGSK3BABL1KMT2A | |
| SCHEMBL18920 | 0.65 | GSK3A (0.39) | GSK3AGSK3BABL1KMT2A | |
| Hydrochloric Acid SCHEMBL6025174 | 0.64 | GSK3A (0.37) | GSK3AGSK3BABL1KMT2A | |
| Hydrochloric Acid SCHEMBL28537243 | 0.64 | GSK3A (0.37) | GSK3AGSK3BABL1KMT2A | |
| SCHEMBL660464 | 0.63 | AHR (0.49) | GSK3AGSK3BAURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |