SCHEMBL7913623

SCHEMBL7913623

CCC1CCC(CCC2CCC(c3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.36
ESR2 Q92731 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
OPRL1 P41146 11/20 0.32
TRPV3 Q8NET8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736323 1.00 CYP2C9 (0.36) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL18512508 0.95 CYP2C9 (0.33) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8860603 0.95 TRPV3 (0.34) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL9763946 0.95 TRPV3 (0.34) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL14526167 0.91 CYP2C9 (0.31) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7516369 0.90 CYP2C9 (0.45) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL3437354 0.90 TRPV3 (0.32) ALDH1A1TRPV3
SCHEMBL8452536 0.90 CYP2C9 (0.45) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL18512507 0.90 TRPV3 (0.32) ALDH1A1TRPV3
SCHEMBL8736434 0.90 TRPV3 (0.32) ALDH1A1TRPV3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457869-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2019-10-29 US disclosed
US-20180037818-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-02-08 US disclosed
US-8366964-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-02-05 US disclosed
US-8366964-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-02-05 US disclosed
US-20110260104-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO PETROCHEMICAL CORPORATION (JP) 2011-10-27 US disclosed
US-20110260104-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO PETROCHEMICAL CORPORATION (JP) 2011-10-27 US disclosed
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0688754-B1 DICYCLOHEXYLETHYLENE DERIVATIVE CHISSO CORP (JP) 1998-10-07 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0688754-A1 DICYCLOHEXYLETHYLENE DERIVATIVE CHISSO CORPORATION (JP) 1995-12-27 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed
US-5032313-A Trifluorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1991-07-16 US disclosed
EP-0387032-A1 Trifluorobenzene derivatives and liquid crystal compositions containing the same Chisso Corporation (JP) 1990-09-12 EP disclosed