Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913623 | 1.00 | CYP2C9 (0.36) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL18512508 | 0.95 | CYP2C9 (0.33) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL8860603 | 0.95 | TRPV3 (0.34) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL9763946 | 0.95 | TRPV3 (0.34) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL14526167 | 0.91 | CYP2C9 (0.31) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7516369 | 0.90 | CYP2C9 (0.45) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL3437354 | 0.90 | TRPV3 (0.32) | ALDH1A1TRPV3 | |
| SCHEMBL8452536 | 0.90 | CYP2C9 (0.45) | CYP2C9ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL18512507 | 0.90 | TRPV3 (0.32) | ALDH1A1TRPV3 | |
| SCHEMBL8736434 | 0.90 | TRPV3 (0.32) | ALDH1A1TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688754-B1 | DICYCLOHEXYLETHYLENE DERIVATIVE | CHISSO CORP (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0688754-A1 | DICYCLOHEXYLETHYLENE DERIVATIVE | CHISSO CORPORATION (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0387032-A1 | Trifluorobenzene derivatives and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1990-09-12 | — | — | EP | disclosed |