Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913686 | 0.93 | KMT2A (0.54) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL112001 | 0.87 | AKR1C1 (0.59) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL4730607 | 0.87 | AKR1C1 (0.59) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL112002 | 0.87 | AKR1C1 (0.59) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL7913674 | 0.87 | MAPT (0.50) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL7949277 | 0.85 | ALDH1A1 (0.48) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL28258743 | 0.83 | CES2 (0.58) | KMT2AMEN1POLBCES2CES1 | |
| Nitrous Acid SCHEMBL4946663 | 0.81 | AKR1C1 (0.52) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL7913676 | 0.80 | BRAF (0.49) | KMT2AMEN1POLBCES2CES1 | |
| SCHEMBL3923058 | 0.79 | TP53 (0.61) | KMT2AMEN1POLBTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218501-B1 | N-HYDROXYHYDROCARBYL-SUBSTITUTED MALEIMIDE POLYMER OR POLYIMIDE ESTERIFIED WITH CINNAMIC ACID DERIVATIVE | CHEIL INDUSTRIES INC. (KR) | 2001-04-17 | — | — | US | disclosed |