Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913580 | 0.88 | LTA4H (0.47) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| SCHEMBL28509572 | 0.87 | LTA4H (0.46) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Hydrochloric Acid SCHEMBL29054359 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Iodide SCHEMBL29054422 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Iodide SCHEMBL29054366 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Bromide SCHEMBL29054354 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Hydrochloric Acid SCHEMBL29054373 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Iodide SCHEMBL29054382 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Hydrochloric Acid SCHEMBL29054350 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A | |
| Iodide SCHEMBL29054367 | 0.85 | LTA4H (0.45) | CYP2D6HTR1ASCN1ASLC6A3SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |