Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626986 | 0.98 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM3MEN1 | |
| SCHEMBL9523751 | 0.77 | CHRM2 (0.41) | CHRM1CHRM2CHRM4CHRM3MEN1 | |
| Hydrochloric Acid SCHEMBL8935473 | 0.75 | PEPD (0.43) | CHRM1CHRM2CHRM4CHRM3MEN1 | |
| Bromide SCHEMBL9293238 | 0.75 | CHRM2 (0.37) | CHRM1CHRM2CHRM4CHRM3MEN1 | |
| SCHEMBL8935481 | 0.72 | CHRM2 (0.36) | CHRM1CHRM2CHRM4CHRM3MEN1 | |
| SCHEMBL12043270 | 0.72 | CHRM2 (0.63) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL7430050 | 0.72 | CHRM2 (0.63) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL7493133 | 0.71 | CHRM2 (0.42) | CHRM1CHRM2CHRM4CHRM3MEN1 | |
| SCHEMBL4339192 | 0.71 | CHRM2 (0.42) | CHRM1CHRM2CHRM4CHRM3MEN1 | |
| SCHEMBL4762996 | 0.71 | CHRM2 (0.42) | CHRM1CHRM2CHRM4CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871445-A4 | COMPOSITION FOR TREATING PAIN | LILLY CO ELI (US) | 2001-01-10 | — | — | EP | claimed |
| JP-2000501709-A | — | — | 2000-02-15 | — | — | JP | claimed |
| EP-0871445-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | claimed |
| WO-1997020561-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1997-06-12 | — | — | WO | claimed |