Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15341643 | 0.90 | ALDH1A1 (0.46) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8935473 | 0.79 | PEPD (0.43) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| Bromide SCHEMBL9293238 | 0.79 | CHRM2 (0.37) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL8935492 | 0.78 | CHRM2 (0.46) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL7330432 | 0.77 | CHRM1 (0.42) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL7913837 | 0.77 | CHRM1 (0.45) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL8935481 | 0.77 | CHRM2 (0.36) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL7435928 | 0.76 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL4339192 | 0.75 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL7493133 | 0.75 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338723-B1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5110828-A | Treatment or prophylaxis of dementia | BEECHAM GROUP P.L.C. (GB) | 1992-05-05 | — | — | US | disclosed |
| EP-0338723-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | disclosed |