Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233108 | 0.85 | GLO1 (0.38) | NPSR1GLO1GAAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL28148061 | 0.82 | NPSR1 (0.46) | NPSR1GLO1GAAALDH1A1MEN1 | |
| SCHEMBL10787532 | 0.79 | ALDH1A1 (0.62) | NPSR1GLO1GAAALDH1A1MEN1 | |
| SCHEMBL2648919 | 0.79 | NPSR1 (0.43) | NPSR1GLO1GAAALDH1A1MEN1 | |
| SCHEMBL21986966 | 0.76 | GLO1 (0.56) | NPSR1GLO1GAAALDH1A1MEN1 | |
| SCHEMBL3590883 | 0.75 | HCAR2 (0.38) | NPSR1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11396128 | 0.74 | SMN1; SMN2 (0.44) | GAAALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4629960 | 0.73 | MAPT (0.57) | GAAALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL15214492 | 0.72 | ALDH1A1 (0.70) | NPSR1GLO1GAAALDH1A1MEN1 | |
| SCHEMBL27834732 | 0.72 | NPSR1 (0.40) | NPSR1GLO1GAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218547-B1 | 1-phenyl-benzimidazole compounds and their use as GABA-a receptor modulators | NEUROSEARCH A/S (DK) | 2001-04-17 | — | — | US | disclosed |