Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659172 | 0.89 | MEN1 (0.57) | MAPTMEN1KMT2AHSD17B10TDP1 | |
| SCHEMBL7916053 | 0.84 | ALDH1A1 (0.54) | MAPTMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL6689955 | 0.82 | HPGD (0.53) | MAPTMEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL1509290 | 0.81 | HSD17B10 (0.54) | MAPTMEN1KMT2AHSD17B10TDP1 | |
| Phosphine SCHEMBL28283987 | 0.80 | HSD17B10 (0.52) | MAPTMEN1KMT2AHSD17B10TDP1 | |
| Ammonia Solution, Strong SCHEMBL28268609 | 0.80 | HSD17B10 (0.52) | MAPTMEN1KMT2AHSD17B10TDP1 | |
| SCHEMBL3055253 | 0.76 | TSHR (0.44) | MEN1KMT2AHSD17B10TDP1TSHR | |
| SCHEMBL2676616 | 0.76 | HPGD (0.47) | MAPTMEN1KMT2AHSD17B10TDP1 | |
| SCHEMBL27651310 | 0.76 | HSD17B10 (0.52) | MEN1KMT2AHSD17B10TDP1TSHR | |
| SCHEMBL2676973 | 0.75 | HPGD (0.46) | MAPTMEN1KMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207809-B1 | CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND | CLARIANT GMBH (DE) | 2001-03-27 | — | — | US | disclosed |