SCHEMBL7914124

SCHEMBL7914124

O=[N+]([O-])c1ccc(P(=O)(O)CCc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
CFTR P13569 1/20 0.49
SIGMAR1 Q99720 1/20 0.48
TSHR P16473 2/20 0.47
ANPEP P15144 1/20 0.46
ERAP2 Q6P179 1/20 0.46
ERAP1 Q9NZ08 1/20 0.46
MAPT P10636 3/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
MAOA P21397 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914116 0.94 CFTR (0.53) SMN1; SMN2NPC1RAB9ATAAR1MEN1
SCHEMBL27583120 0.78 ALDH1A1 (0.65) SMN1; SMN2NPC1RAB9ATAAR1MEN1
SCHEMBL2421099 0.77 TSHR (0.61) SMN1; SMN2NPC1RAB9ACYP1A2CYP2C19
SCHEMBL13946243 0.76 CYP1A2 (0.67) SMN1; SMN2NPC1RAB9ATAAR1MEN1
SCHEMBL1899932 0.76 TSHR (0.46) SMN1; SMN2NPC1RAB9AMEN1KMT2A
SCHEMBL31684238 0.75 ALDH1A1 (0.56) SMN1; SMN2NPC1RAB9AMEN1KMT2A
Benzylphosphonic Acid SCHEMBL27466353 0.74 CYP1A2 (0.60) SMN1; SMN2NPC1RAB9ATAAR1MEN1
Nitrobenzene SCHEMBL28658933 0.72 ALDH1A1 (0.76) NPC1RAB9AMEN1KMT2ACYP1A2
Nitrobenzene SCHEMBL5277749 0.72 ALDH1A1 (0.76) NPC1RAB9AMEN1KMT2ACYP1A2
Nitrobenzene SCHEMBL13277687 0.72 ALDH1A1 (0.76) NPC1RAB9AMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6180548-B1 Environment-purifying material and its manufacturing method AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2001-01-30 US disclosed