Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707763 | 0.83 | NR4A2 (0.44) | PIK3CGF7F3DYRK1ACYP2A6 | |
| SCHEMBL28538700 | 0.74 | BACE1 (0.44) | NPC1RAB9ACYP2A6ALDH1A1MAPT | |
| SCHEMBL2491067 | 0.74 | PLAU (0.47) | NPC1RAB9ADYRK1AALDH1A1MAPT | |
| SCHEMBL2491479 | 0.69 | NPC1 (0.51) | NPC1RAB9ADYRK1AALDH1A1CYP1A2 | |
| SCHEMBL2493204 | 0.69 | RAB9A (0.55) | NPC1RAB9ACYP2A6ALDH1A1MAPT | |
| SCHEMBL23913875 | 0.69 | SCN10A (0.44) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL2494247 | 0.69 | APP (0.48) | NPC1RAB9APSMB5ALDH1A1MAPT | |
| SCHEMBL405106 | 0.69 | ALDH1A1 (0.41) | NPC1RAB9APIK3CGALDH1A1MAPT | |
| SCHEMBL6647893 | 0.68 | TDP1 (0.49) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL21672373 | 0.67 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431439-A | Method for preparing 2-formylaryl (phosphinic) phosphine/phosphoramide compound | 岳阳凯茂化工材料有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-113214178-B | 3-aryl substituted anthranilic anhydride derivative and preparation method thereof | 广东工业大学 | 2022-05-13 | — | — | CN | claimed |
| CN-113214178-A | 3-aryl substituted anthranilic anhydride derivative and preparation method thereof | 广东工业大学 | 2021-08-06 | — | — | CN | claimed |
| CN-119431439-A | Method for preparing 2-formylaryl (phosphinic) phosphine/phosphoramide compound | 岳阳凯茂化工材料有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-113214178-B | 3-aryl substituted anthranilic anhydride derivative and preparation method thereof | 广东工业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-109912503-B | Synthetic method of 2, 3-diacyl quinoline compound | 江南大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-110204487-B | Synthesis method of quinoline derivative | 江南大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-113214178-A | 3-aryl substituted anthranilic anhydride derivative and preparation method thereof | 广东工业大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-109776488-B | Synthesis method of alpha-ketoamide compound with ortho-aldehyde group | 江南大学 | 2021-04-27 | — | — | CN | disclosed |
| EP-3233844-A1 | 3-(6-ALKOXY-5-CHLOROBENZO[D]ISOXAZOL-3-YL)PROPANOIC ACID USEFUL AS KYNURENINE MONOOXYGENASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097144-A1 | 3-(6-ALKOXY-5-CHLOROBENZO[D]ISOXAZOL-3-YL)PROPANOIC ACID USEFUL AS KYNURENINE MONOOXYGENASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| EP-0741702-A4 | PROCESS FOR PREPARING 2-OXINDOLE-1-CARBOXAMIDES | CATALYTICA INC (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0741702-A1 | PROCESS FOR PREPARING 2-OXINDOLE-1-CARBOXAMIDES | CATALYTICA, INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020574-A1 | PROCESS FOR PREPARING 2-OXINDOLE-1-CARBOXAMIDES | CATALYTICA, INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| CN-1071917-A | Quinazoline derivant as human immunodeficiency virus reversed transcriptive enzyme antagonist | MERCK & CO INC (US) | 1993-05-12 | — | — | CN | disclosed |