Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835330 | 0.85 | GLA (0.67) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL7914283 | 0.84 | GLA (0.63) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL1104933 | 0.81 | GLA (0.72) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL7917998 | 0.81 | GLA (0.50) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL2300739 | 0.79 | NPC1 (0.66) | GLAMEN1KMT2AMIFKDM4E | |
| SCHEMBL1094715 | 0.79 | GLA (1.00) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL557165 | 0.78 | CA12 (0.73) | GLAMEN1KMT2ACA9KDM4E | |
| SCHEMBL12386518 | 0.77 | NPC1 (0.78) | GLAMEN1KMT2AMIFKDM4E | |
| SCHEMBL10024034 | 0.76 | NPC1 (0.62) | GLAMEN1KMT2AMIFKDM4E | |
| SCHEMBL2303012 | 0.76 | NPC1 (0.67) | GLAMEN1KMT2AMIFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-B1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | ROLIC AG (CH) | 1999-12-01 | — | — | EP | disclosed |